The healthiest mushrooms have high levels of antioxidants and beta-glucans, which help support the immune system and protect the body against age-related disease. To receive the most benefits from these mushrooms, it is important utilize them for several weeks and some as an ongoing daily supplement. This is because the mushrooms' compounds build up in the body over time. So it's best to use supplements on a consistent basis, such as taking two tablespoons of mushrooms daily